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Biomicrofluidics / Volume 5 / Issue 1 / SPECIAL TOPIC: BIOLOGICAL MICROFLUIDICS IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE (GUEST EDITOR: SUWAN JAYASINGHE)

Biomicrofluidics 5, 013403 (2011); http://dx.doi.org/10.1063/1.3567097 (19 pages)

Electrospinning jets and nanofibrous structures

Koyal Garg and Gary L. Bowlin

Department of Biomedical Engineering, Virginia Commonwealth University, Virginia 23284, USA

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(Received 10 September 2010; accepted 8 February 2011; published online 30 March 2011)

Electrospinning is a process that creates nanofibers through an electrically charged jet of polymer solution or melt. This technique is applicable to virtually every soluble or fusible polymer and is capable of spinning fibers in a variety of shapes and sizes with a wide range of properties to be used in a broad range of biomedical and industrial applications. Electrospinning requires a very simple and economical setup but is an intricate process that depends on several molecular, processing, and technical parameters. This article reviews information on the three stages of the electrospinning process (i.e., jet initiation, elongation, and solidification). Some of the unique properties of the electrospun structures have also been highlighted. This article also illustrates some recent innovations to modify the electrospinning process. The use of electrospun scaffolds in the field of tissue engineering and regenerative medicine has also been described.

© 2011 American Institute of Physics

Article Outline

  1. ELECTROSPINNING
  2. HISTORICAL BACKGROUND OF ELECTROSPINNING
  3. MODELING OF THE ELECTROSPINNING PROCESS
    1. Jet initiation
    2. Jet thinning
    3. Jet instabilities
    4. Jet solidification
  4. PROPERTIES OF ELECTROSPUN NANOFIBERS
    1. Fiber dimension and morphology
    2. Porosity
    3. Surface structure
    4. Chain conformation and crystallinity of nanofibers
  5. ELECTROSPINNING INNOVATIONS AND MODIFICATIONS
    1. Coaxial electrospinning
    2. Multilayer and mixed electrospinning
    3. Forced air assisted electrospinning
    4. Air-gap electrospinning
  6. APPLICATIONS IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE
    1. Polymeric scaffolds for tissue engineering
    2. Nanofiber matrices for release of drugs
  7. CONCLUSION

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KEYWORDS and PACS

Keywords

biomedical equipment, electrospinning, elongation, jets, nanofibres, solidification, tissue engineering

PACS

  • 81.05.Lg

    Polymers and plastics; rubber; synthetic and natural fibers; organometallic and organic materials

  • 81.40.Lm

    Deformation, plasticity, and creep

  • 62.20.F-

    Deformation and plasticity

  • 87.85.Lf

    Tissue engineering

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.3567097

PUBLICATION DATA

ISSN

1932-1058 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
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