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Biomicrofluidics 4, 026502 (2010); doi:10.1063/1.3259624 (5 pages)

Fabrication of microfluidic devices using polydimethylsiloxane

James Friend and Leslie Yeo

Department of Mechanical and Aerospace Engineering, MicroNanophysics Research Laboratory, Monash University, Melbourne VIC 3800 Australia

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(Received 6 October 2009; accepted 16 October 2009; published online 15 March 2010)

Polydimethylsiloxane (PDMS) is nearly ubiquitous in microfluidic devices, being easy to work with, economical, and transparent. A detailed protocol is provided here for using PDMS in the fabrication of microfluidic devices to aid those interested in using the material in their work, with information on the many potential ways the material may be used for novel devices.

© 2010 American Institute of Physics

Article Outline

  1. INTRODUCTION
  2. METHOD
    1. PDMS
    2. Casting
      1. Molds
      2. Casting, curing, and releasing PDMS from the mold
    3. Bonding
    4. Interfacing and integration

KEYWORDS and PACS

PACS

  • 87.80.Ek

    Mechanical and micromechanical techniques

  • 85.85.+j

    Micro- and nano-electromechanical systems (MEMS/NEMS) and devices

  • 07.10.Cm

    Micromechanical devices and systems

PUBLICATION DATA

ISSN:

1932-1058 (print)  
1932-1058 (online)

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Figures (click on thumbnails to view enlargements)

FIG.1
Process of making microfluidic devices with PDMS. (Enhanced online.)

FIG.1 Download High Resolution Image (.zip file) | Export Figure to PowerPoint

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