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Biomicrofluidics / Volume 1 / Issue 4 / REGULAR ARTICLES

Biomicrofluidics 1, 044101 (2007); http://dx.doi.org/10.1063/1.2795392 (12 pages)

Real-time detection, control, and sorting of microfluidic droplets

Xize Niu, Mengying Zhang, Suili Peng, Weijia Wen, and Ping Sheng

Department of Physics and Institute of Nano Science and Technology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong

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(Received 29 August 2007; accepted 18 September 2007; published online 3 October 2007)

We report the design and implementation of capacitive detection and control of microfluidic droplets in microfluidic devices. Integrated microfluidic chip(s) with detection/control circuit enables us to monitor in situ the individual volume of droplets, ranging from nanoliter to picoliter, velocity and even composition, with an operation frequency of several kilohertz. Through electronic feedback, we are able to easily count, sort, and direct the microfluidic droplets. Potential applications of this approach can be employed in the areas of biomicrofluidic processing, microchemical reactions as well as digital microfluidics.

© 2007 American Institute of Physics

Article Outline

  1. INTRODUCTION
  2. MATERIALS, METHODS, AND EXPERIMENTAL SETUP
    1. Microfluidic chip
    2. Testing mechanism and circuit design
  3. RESULTS AND DISCUSSION
    1. Single droplet scanning
    2. Simplified electrode structure for droplet size and speed detection
    3. Droplet composition detection
    4. Directional flow control of droplets
  4. CONCLUDING REMARKS

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KEYWORDS and PACS

Keywords

drops, flow control, microchannel flow, microfluidics

PACS

  • 47.85.Np

    Fluidics

  • 47.55.db

    Drop and bubble formation

  • 47.85.L-

    Flow control

  • 47.60.-i

    Flow phenomena in quasi-one-dimensional systems

  • 47.61.Fg

    Flows in micro-electromechanical systems (MEMS) and nano-electromechanical systems (NEMS)

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.2795392

PUBLICATION DATA

ISSN

1932-1058 (print)  
1932-1058 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
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