Calcium carbonate polymorph control using droplet-based microfluidics
Alexandra Yashina, Fiona Meldrum, and Andrew deMello
In this study, droplet-based microfluidics is used to study the complex and poorly characterized polymorphic crystalline behaviour of a very important biomineral - calcium carbonate. Polymorphism in inorganic and organic (molecular) crystals is an important and rapidly expanding area of research, with broad implications in pharmaceutical processing and drug formulation.
CO2 dissolution in water using long serpentine microchannels
Thomas Cubaud, Martin Sauzade, and Ruopeng Sun
Cubaud and co-workers study dynamical transitions and map morphological regimes in gas-liquid flow when a dissolving gas (such as CO2) is used.This study of 'carbonated' microflows is a growing area of research with very practical implications in several areas, ranging from geochemistry in sub-surface reservoirs to fuel cell technology.
Utilizing microfluidics to synthesize polyethylene glycol microbeads for Förster resonance energy transfer based glucose sensing
Chaitanya Kantak, Qingdi Zhu, Sebastian Beyer, Tushar Bansal, and Dieter Trau
A Förster Resonance Energy Transfer (FRET)-based in vitro glucose assay entirely encapsulated within spherical photo-polymerized microparticles fabricated using droplet microfluidics is presented. Such microparticles can be used as low cost yet sensitive in vitro biosensors for applications requiring spatially resolved sensing, such as cell culture and tissue engineering.
Slow growth of the Rayleigh-Plateau instability in aqueous two phase systems
Sam D. Geschiere, Iwona Ziemecka, Volkert van Steijn, Ger J. M. Koper, Jan H. van Esch, and Michiel T. Kreutzer
Geschiere and co-workers provide experimental evidence of a counterintuitive fluid phenomenon - retarded instability of fluid threads of a polymer solution (PEG) when dispensed into another solution of an incompatible polymer (Dextran). This study has important practical implications in the design of microfluidic devices that involve breakup of fluid threads with very low interfacial tensions and diffuse fluid interfaces.
Field-free particle focusing in microfluidic plugs
G. K. Kurup and Amar S. Basu
Kurup and Basu describe a field-free method of microparticle concentration within droplets that relies on competition between hydrodynamic drag and sedimentation within droplets. They analyse the relevant physics and arrive at a dimensionless parameter predicting device performance, which can be directly used in design and optimization studies.